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Mechanism of Action:
Vardenafil is a PDE5 inhibitor. It works by increasing blood flow to the penis during sexual stimulation.
Unlike sildenafil (), vardenafil does not have an effect on PDE6, which means it does not cause vision-related adverse effects.
Medical Use:
Vardenafil is taken by mouth, usually about 60 minutes before sexual activity.
It helps men achieve and maintain an erection by improving blood flow to the penis.
Indications and Contraindications:
Vardenafil’s indications and contraindications are similar to other PDE5 inhibitors (such as sildenafil and tadalafil).
It may also be effective in treating premature ejaculation, increasing the time from penetration to ejaculation.
Side Effects:
Common side effects include nausea, while infrequent side effects include abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism (a painful, prolonged erection).
Rarely, vardenafil use may lead to a heart attack.
The U.S. FDA has added a warning about possible sudden hearing loss to vardenafil’s drug labels.
Remember to use vardenafil under the guidance of a healthcare provider, and be aware of potential side effects and interactions with other medications