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Raloxifene, also known by its brand name Evista, is a medication used to prevent and treat osteoporosis in postmenopausal women and those on glucocorticoids. Here are some key points about Raloxifene:
Mechanism of Action:
Raloxifene is a selective estrogen receptor modulator (SERM).
It has estrogenic effects in bone (beneficial for osteoporosis) and antiestrogenic effects in the breasts and uterus (reducing the risk of breast cancer).
Medical Uses:
Osteoporosis: Raloxifene is used for the treatment and prevention of osteoporosis in postmenopausal women. The recommended dosage is 60 mg/day for both prevention and treatment.
Breast Cancer Risk Reduction: It is also used to reduce the risk of invasive breast cancer in women at high risk.
Side Effects:
Common side effects include hot flashes, leg cramps, swelling, and joint pain.
Severe side effects may include blood clots and stroke.
Warnings and Precautions:
Pregnancy: Use during pregnancy may harm the baby.
Menstrual Symptoms: Raloxifene may worsen menstrual symptoms.
Allergic Reactions: Seek immediate medical help if you experience hives, blisters, trouble breathing, or swelling.
Regular Monitoring: Regular visits with your doctor are essential to assess progress and manage any potential side effects.
Remember to take Raloxifene as prescribed and consult your healthcare provider if you have any concerns or questions123.
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